The main difference between finasteride and dutasteride is that finasteride is selective for type II 5AR while dutasteride inhibits both type I and type II. Dutasteride not only blocks both types of receptors but also does so much more effectively.
Which is better finasteride or dutasteride?
Finasteride Blocks Approximately 70 Percent of DHT, Whereas Dutasteride Blocks 90 Percent or More. One reason that dutasteride may be slightly more effective than finasteride is that it appears to block more testosterone from being converted into DHT, the hormone that causes male pattern baldness.
Can I take finasteride and dutasteride together?
No interactions were found between dutasteride and finasteride.
Should I take dutasteride or finasteride for hair loss?
Studies have found that dutasteride is more effective at treating male pattern baldness. This medication is not only shown to be potentially more effective at treating hair loss but also shows the same rate and types of side effects as finasteride.
Which has less side effects finasteride or dutasteride?
Finasteride had fewer sexual side effects compared to dutasteride in men with BPH. Sexual side effects resulted in more withdrawals from dutaseride therapy compared to finasteride.
Is dutasteride safe long term?
The safety and tolerability of a drug is an important factor for long-term consumption. Dutasteride seems to be safe in long-term studies, but the importance of proper patient counseling on related sexual adverse events must be considered.
Why is dutasteride not FDA approved?
The GlaxoSmithKline (GSK) drug Avodart (dutasteride), already approved for treatment in men with enlarged prostate glands, has been rejected by the FDA for the additional indication of reducing the risk of prostate cancer. An FDA advisory panel voted 14-2 on Dec. 1 to recommend against the expanded use of the drug.
Do you shed on dutasteride?
There is not usually a shedding period if you are switching from an oral Finasteride or Dutasteride to topical Finasteride or Dutasteride, or from a topical to an oral form.
Can you take dutasteride every other day?
Dutasteride comes as a capsule to take by mouth. It is usually taken once a day with or without food. Take dutasteride at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
What are the side effects of taking dutasteride?
- problems with ejaculation.
- a stuffy and runny nose.
- backache.
- dizziness.
- headache.
- diarrhea.
- generalized weakness.
- altered interest in having sexual intercourse.
Is saw palmetto better than finasteride?
In the end, 38% of those who took saw palmetto had an improvement in their hair loss, compared with 68% of those who took finasteride. This finding suggests that both treatments had an effect but that finasteride was more effective.
What happens when you stop taking dutasteride?
If you stop taking the drug or don’t take it at all: If you don’t take or stop taking dutasteride, you may have increased symptoms such as difficulty starting to urinate, straining while trying to urinate, a weak urine flow, frequent urges to urinate, or more frequent need to wake up during the night to urinate.
Is finasteride enough to stop hair loss?
It causes individual hair follicles to shrink over time, which thins the hair and ages hair follicles until they fall out. By reducing the production of DHT in the body — a daily dose of 1 mg Finasteride is enough to reduce the amount of DHT in the scalp by more than 60% — Finasteride halts this hair loss process.
Is there an alternative to finasteride?
Topical minoxidil (Rogaine®) is also FDA-approved for hair loss and available over-the-counter. Given that it has a similar mechanism of action to finasteride, you may be wondering why dutasteride is not approved for the treatment of hair loss.
Are dutasteride side effects permanent?
These sexual adverse reactions are associated with dutasteride treatment (including monotherapy and combination with tamsulosin). These adverse reactions may persist after treatment discontinuation. The role of dutasteride in this persistence is unknown.
Which finasteride is best?
“There are dose-ranging clinical studies that show finasteride 1mg is just as good as finasteride 5mg,” explains Dr. Jerry Shapiro, one of the Keeps medical advisors. “So there’s no reason to prescribe a higher dosage.” In other words, finasteride 1mg is wholly sufficient.