Diabetes insipidus is present when the
serum osmolality
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is raised (>,295 milliOsmol/kg) with inappropriately dilute urine (urine osmolality <,700 milliOsmol/kg). The serum sodium is often elevated due to excess free water losses.
Does diabetes insipidus cause low sodium?
Diabetes insipidus can cause an imbalance in minerals in your blood, such as sodium and potassium (electrolytes), that maintain the fluid balance in your body. Symptoms of an electrolyte imbalance may include: Weakness.
Does diabetes insipidus cause high sodium?
Certain blood and urine tests can point to a diagnosis of diabetes insipidus such as a high sodium level (hypernatraemia) and high concentration of the blood (serum or plasma osmolality), along with a low urine concentration (urine osmolality).
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What is the sodium level in diabetes insipidus?
Diabetes insipidus (DI) presents clinically as pathologic polyuria and polydipsia and if volume depletion is present, serum sodium is greater than145 mEq/L and serum osmolality is greater than 300 mOsm/kg.
What lab values indicate diabetes insipidus?
A urine specific gravity of 1.005 or less and a urine osmolality less than 200 mOsm/kg is the hallmark of diabetes insipidus. Random plasma osmolality generally is greater than 287 mOsm/kg.