Ivermectin has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of teratogenicity, but at doses that were also maternotoxic to the pregnant female. The manufacturer considers ivermectin contraindicated during pregnancy.
Is it safe to give ivermectin to pregnant cows?
Ivermectin is reported as safe drug in ruminants during pregnancy.
Can I use ivermectin while breastfeeding?
Data from four nursing mothers indicate that ivermectin is poorly excreted into breast milk after oral administration. Amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
What does pregnancy category C mean?
Category C: Animal studies have shown risk to the fetus, there are no controlled studies in women, or studies in women and animals are not available.
Does ivermectin cause miscarriage?
It is unclear whether exposure to ivermectin during pregnancy increases the risk of spontaneous abortions and stillbirths (odds ratio [OR] 1·15 [95% CI 0·75–1·78] with very low certainty of evidence for the four observational studies and 0·62 [0·18–2·14] with very low certainty of evidence for the RCT) or congenital …
Can you worm a pregnant cow?
The pregnant cows can be dewormed in the fall. The cows can be expected to winter better, have a higher conception rate the next breeding season, and wean heavier calves.
Can babies take ivermectin?
Ivermectin has been approved for the treatment of scabies in adults and children >, 15 kg, but its use is off-label in infants and children weighing <, 15 kg.
How long does ivermectin stay in breastmilk?
Ivermectin was detected in milk within 1 hour after the dose and for 72 hours after the dose. The average peak milk level was 15 mcg/L (range 11 to 21 mcg/L) and occurred 4 hours after the dose in 2 women, 6 hours in another and 12 hours after the dose in the fourth.
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Does ivermectin cause weight gain?
Mean total weight gain was 33.9 kg (74.6 lb) greater for ivermectin-treated calves than for untreated control calves (P <, 0.02): a 34% increase.