What happens after methotrexate for ectopic pregnancy?

What happens after you take methotrexate for ectopic pregnancy?

After treatment, you may have mild abdominal pain or cramping. Some women also have nausea and vomiting, diarrhea, or fatigue. There are some cases when you can’t use methotrexate.

How long does it take for an ectopic pregnancy to dissolve after having methotrexate?

The average time of resolution for ectopic pregnancy was 32 days for single dose of methotrexate and 58 days for those receiving two doses or more.

What should I avoid after methotrexate for ectopic pregnancy?

Yes, during treatment with methotrexate you should avoid the following:
  • Heavy exercise.
  • Sexual intercourse.
  • Alcohol.
  • Vitamins and foods that contain folic acid, including fortified cereal, enriched bread and pasta, peanuts, dark green leafy vegetables, orange juice, and beans.

How long do you bleed after methotrexate?

A few days after the injection, it is usual to begin to bleed and this bleeding can last between a few days and up to 6 weeks. It is usual to have some discomfort and pain initially but as long as this is not severe. If your pain is severe, please come into hospital immediately.

Can your tube rupture after methotrexate?

There is still around a one in 14 chance of your fallopian tubes splitting open (rupture) after medical treatment with methotrexate, even if your hCG levels are going down. Therefore, be aware of the potential symptoms of a rupture and be ready to call an ambulance if you think a rupture has occurred.

Can hCG go up after methotrexate?

Serum hCG levels rise immediately after MTX administration for ectopic pregnancy in 50%-70% of patients.

How fast does hCG drop after methotrexate?

Conclusions. We have found that a fall in serum hCG between days 0–4 after single-dose methotrexate treatment of ectopic pregnancy (where the pre-treatment serum hCG is ≤3000 IU/L), predicts treatment success in 85% of cases, with no further intervention required (medical or surgical).

How do I know if methotrexate is working for ectopic pregnancy?

To see if the methotrexate has worked, you will need to return to the clinic to have a blood test 1 week after receiving it. You will need to repeat this test once a week until we can see that there is no more pregnancy hormone left in your body. When this happens, we know that the medication has worked.

At what week would an ectopic pregnancy rupture?

The structure containing the fetus typically ruptures after about 6 to 16 weeks, long before the fetus is able to live on its own. When an ectopic pregnancy ruptures, bleeding may be severe and even threaten the life of the woman.

How can you tell if methotrexate is working?

Official Answer. If methotrexate is working for your rheumatoid arthritis (RA), you should experience fewer severe arthritis symptoms (such as fewer swollen or painful joints) and be able to move and complete day-to-day activities more easily.

How long did you bleed after methotrexate for ectopic?

It should not be severe and lasts four to 12 hours. You can also expect to have vaginal bleeding which is light or like a period. This lasts a few days but you may have a brown discharge for two to three weeks.


How long does methotrexate stay in your system?

The estimated length of time it takes for methotrexate to be removed from your body is: For low dose methotrexate ranges from 16.5 hours to 55 hours. For high dose methotrexate ranges from 44 hours to 82.5 hours.

Does bleeding mean methotrexate is working?

The bleeding may start soon after you get your first dose of methotrexate, or it may take a little while to start. So, bleeding and cramping aren’t sufficient signs to know that the medication is working or not.

How do I know if my fallopian tube has ruptured?

These symptoms include:
  1. Pain during intercourse.
  2. Irregular vaginal bleeding or spotting.
  3. Cramping or pain on one side, or in the lower abdomen.
  4. Rapid heartbeat.

When can I return to work after an ectopic pregnancy?

Return to work two to six weeks after a laparotomy and one week after a laparoscopy. 12. Avoid vigorous exercise and lifting more than 10 pounds until your incision site(s) are fully healed.